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근거중심한의약 DB

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Title

Topical vitamin A treatment of recalcitrant common warts.

Authors

Gaston A, Garry RF.

Journal

Virol J.

Year

2012

Vol (Issue)

9

Page

21.

doi

10.1186/1743-422X-9-21.

PMID

22251397

Url

http://www.ncbi.nlm.nih.gov/pubmed/22251397

MeSH

Administration, Topical
Adult
Female
Hand/pathology
Humans
Skin Diseases, Viral/drug therapy*
Skin Diseases, Viral/pathology
Treatment Outcome
Vitamin A/administration & dosage*
Warts/drug therapy*
Warts/pathology

Keywords

한글 키워드

KMCRIC summary and commentary

없음

Korean Study

Abstract

BACKGROUND:
Common warts (verruca vulgaris) are benign epithelial proliferations associated with human papillomavirus (HPV) infection. Salicylic acid and cryotherapy are the most frequent treatments for common warts, but can be painful and cause scarring, and have high failure and recrudescence rates. Topical vitamin A has been shown to be a successful treatment of common warts in prior informal studies.
CASE:
The subject is a healthy, physically-active 30 old female with a 9 year history of common warts on the back of the right hand. The warts resisted treatment with salicylic acid, apple cider vinegar and an over-the-counter blend of essential oils marketed for the treatment of warts. Daily topical application of natural vitamin A derived from fish liver oil (25,000 IU) led to replacement of all the warts with normal skin. Most of the smaller warts had been replaced by 70 days. A large wart on the middle knuckle required 6 months of vitamin A treatment to resolve completely.
CONCLUSION:
Retinoids should be further investigated in controlled studies to determine their effectiveness in treating common warts and the broad range of other benign and cancerous lesions induced by HPVs.

국문초록

Language

영어

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