KMCRIC

Acupuncture and physical exercise for affective symptoms and health-related quality of life in polycystic ovary syndrome: Secondary analysis from a randomized controlled trial.

Stener-Victorin E, Holm G, Janson PO, Gustafson D, Waern M.

BMC Complement Altern Med.

2013

13(1)

131.

10.1186/1472-6882-13-131.

23763822

http://www.ncbi.nlm.nih.gov/pubmed/23763822

Acupuncture Therapy*
Adult
Affective Symptoms/therapy*
Anxiety/therapy*
Depression/therapy*
Exercise*/psychology
Female
Humans
Polycystic Ovary Syndrome/psychology*
Polycystic Ovary Syndrome/therapy
Quality of Life*
Surveys and Questionnaires

Acupuncture; Anxiety; Depression; Exercise; Health-related quality of life; Polycystic ovary syndrome

침 치료; 불안; 우울증; 운동; 건강 관련 삶의 질; 다낭성 난소 증후군

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BACKGROUND: Women with polycystic ovary syndrome (PCOS) have symptoms of depression and anxiety and impaired health related quality of life (HRQoL). Here we test the post-hoc hypothesis that acupuncture and exercise improve depression and anxiety symptoms and HRQoL in PCOS women.
METHODS: Seventy-two PCOS women were randomly assigned to 16 weeks of 1) acupuncture (n = 28); 2) exercise (n = 29); or 3) no intervention (control) (n = 15). Outcome measures included: change in Montgomery Asberg Depression Rating Scale (MADRS-S), Brief Scale for Anxiety (BSA-S), Swedish Short-Form 36 (SF-36), and PCOS Questionnaire (PCOSQ) scores from baseline to after 16-week intervention, and to 16-week post-intervention follow-up.
RESULTS: A reduction in MADRS-S and BSA-S from baseline to 16-weeks post-intervention follow-up was observed for the acupuncture group. The SF-36 domains role physical, energy/vitality, general health perception and the mental component of summary scores improved in the acupuncture group after intervention and at follow-up. Within the exercise group the role physical decreased after treatment, while physical functioning and general health perception scores increased at follow-up. The emotion domain in the PCOSQ improved after 16-weeks of intervention within all three groups, and at follow-up in acupuncture and exercise groups. At follow-up, improvement in the infertility domain was observed within the exercise group.
CONCLUSION: There was a modest improvement in depression and anxiety scores in women treated with acupuncture, and improved HRQoL scores were noted in both intervention groups. While not a primary focus of the trial, these data suggest continued investigation of mental health outcomes in women treated for PCOS.
Trial registration numberClinicalTrials.gov Identifier: NCT00484705.

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