KMCRIC

Digestion-Specific Acupuncture Effect on Feeding Intolerance in Critically Ill Post-Operative Oral and Hypopharyngeal Cancer Patients: A Single-Blind Randomized Control Trial.

Ben-Arie E, Wei TH, Chen HC, Huang TC, Ho WC, Chang CM, Kao PY, Lee YC.

Nutrients.

2021

13(6)

2110.

10.3390/nu13062110.

34205461

http://www.ncbi.nlm.nih.gov/pubmed/34205461

Acupuncture Therapy*
Aged
China
Critical Illness / therapy*
Digestion*
Energy Intake
Energy Metabolism
Humans
Hypopharyngeal Neoplasms / therapy*
Male
Malnutrition / etiology
Malnutrition / therapy
Metoclopramide / therapeutic use
Middle Aged
Mouth Neoplasms / therapy*
Nutritional Support / methods
Postoperative Care / methods*
Single-Blind Method
Treatment Outcome

ICU; acupuncture; critically ill; digestion; energy expenditure (EE); feeding intolerance; hypopharyngeal cancer; oral cancer; postoperative.

침 치료; 중환자; 소화; 에너지 소비; 섭식불내증; 하인두암; 구강암; 수술 후

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Malnourishment is prevalent in patients suffering from head and neck cancer. The postoperative period is crucial in terms of nutritional support, especially after composite resection and reconstruction surgery. These patients present with a number of risk factors that aggravate feeding intolerance, including postoperative status, prolonged immobility, decreased head elevation, mechanical ventilation, and applied sedative agents. Routine management protocols for feeding intolerance include prokinetic drug use and post-pyloric tube insertion, which could be both limited and accompanied by detrimental adverse events. This single-blind clinical trial aimed to investigate the effects of acupuncture in postoperative feeding intolerance in critically ill oral and hypopharyngeal cancer patients. Twenty-eight patients were randomized into two groups: Intervention group and Control group. Interventions were administered daily over three consecutive postoperative days. The primary outcome revealed that the intervention group reached 70% and 80% of target energy expenditure (EE) significantly earlier than the control group (4.00 ± 1.22 versus 6.69 ± 3.50 days, p = 0.012), accompanied by higher total calorie intake within the first postoperative week (10263.62 ± 1086.11 kcals versus 8384.69 ± 2120.05 kcals, p = 0.004). Furthermore, the intervention group also needed less of the prokinetic drug (Metoclopramide, 20.77 ± 48.73 mg versus 68.46 ± 66.56 mg, p = 0.010). In conclusion, digestion-specific acupuncture facilitated reduced postoperative feeding intolerance in oral and hypopharyngeal cancer patients.

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