플러스100%마이너스

  • 화면크기
통합검색

한의약융합데이터센터


근거중심한의약 DB

Home > 한의약융합데이터센터 > 근거중심한의약 DB
Title

긴장성두통에 대한 한약치료: 체계적 문헌고찰 및 메타분석.

Authors

최은지, 권찬영, 한경훈, 김종우, 정선용.

Journal

동의신경정신과학회지.

Year

2015

Vol (Issue)

26(4)

Page

383-406.

doi

10.7231/jon.2015.26.4.383.

PMID

Url

http://www.ndsl.kr/ndsl/commons/util/ndslOriginalView.do?cn=JAKO201512037059039&dbt=JAKO&koi=KISTI1.1003%2FJNL.JAKO201512037059039

MeSH

Keywords

Tension-type headache; Herbal medicine; Randomized controlled trial; Meta-analysis; Systematic review

한글 키워드

긴장성 두통; 한약; 무작위배정 비교 임상시험; 메타분석; 체계적 문헌고찰

KMCRIC summary and commentary

없음

Korean Study

Y

Abstract

Objectives: People with tension-type headache generally take pain relievers, but long term dependency causes problems as well as side effects. The present study aimed to provide clinical evidence of herbal medicine for tension-type headache by systematic review of randomized controlled trials on the effect of herbal medicine for tension-type headache. Methods: Randomized or quasi-randomized controlled trials that verified effects of herbal medicine intervention on patients with tension-type headache were included in the study. A literature search of English, Japanese, Chinese, Korean databases was performed. The selected literature were assessed by Jadad scale and Risk of Bias. Results: Herein, 40 reports were selected from a total of 157. Meta-analyses of 2 trials indicated that the effective rate was significantly higher in the herbal medicine treatment group, as compared to the placebo control (risk ratio: 1.49, 95% confidence interval (CI): 1.23 to 1.80, p<0.0001, I²=0%). Four trials that compared herbal medicine with routine care with routine care only group showed a significantly higher effective rate of benefits for herbal medicine with routine care, as compared to routine care only (RR: 1.57, 95% CI: 1.18 to 2.10, p=0.002, I²=0%). Conclusions: The effective rate was significantly higher than control and adverse events were less in the treatment group. Pattern analysis (辨證) indicated that the studies on wind-fire pattern (風火證) were highest. Yougeun-bang (柔筋方) in prescription and Paeoniae Radix Alba (白芍藥) in medicinal herbs were most used. This finding could be widely utilized in future clinical practice and form the basis for the development of clinical practice guidelines in advance.

국문초록

Language

한국어

첨부파일