근거중심한의약 DB
Home > 한의약융합데이터센터 > 근거중심한의약 DBTitle | 긴장성두통에 대한 한약치료: 체계적 문헌고찰 및 메타분석. |
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Authors | 최은지, 권찬영, 한경훈, 김종우, 정선용. |
Journal | 동의신경정신과학회지. |
Year | 2015 |
Vol (Issue) | 26(4) |
Page | 383-406. |
doi | 10.7231/jon.2015.26.4.383. |
PMID | |
Url | |
MeSH | |
Keywords | Tension-type headache; Herbal medicine; Randomized controlled trial; Meta-analysis; Systematic review |
한글 키워드 | 긴장성 두통; 한약; 무작위배정 비교 임상시험; 메타분석; 체계적 문헌고찰 |
KMCRIC summary and commentary | 없음 |
Korean Study | Y |
Abstract | Objectives: People with tension-type headache generally take pain relievers, but long term dependency causes problems as well as side effects. The present study aimed to provide clinical evidence of herbal medicine for tension-type headache by systematic review of randomized controlled trials on the effect of herbal medicine for tension-type headache. Methods: Randomized or quasi-randomized controlled trials that verified effects of herbal medicine intervention on patients with tension-type headache were included in the study. A literature search of English, Japanese, Chinese, Korean databases was performed. The selected literature were assessed by Jadad scale and Risk of Bias. Results: Herein, 40 reports were selected from a total of 157. Meta-analyses of 2 trials indicated that the effective rate was significantly higher in the herbal medicine treatment group, as compared to the placebo control (risk ratio: 1.49, 95% confidence interval (CI): 1.23 to 1.80, p<0.0001, I²=0%). Four trials that compared herbal medicine with routine care with routine care only group showed a significantly higher effective rate of benefits for herbal medicine with routine care, as compared to routine care only (RR: 1.57, 95% CI: 1.18 to 2.10, p=0.002, I²=0%). Conclusions: The effective rate was significantly higher than control and adverse events were less in the treatment group. Pattern analysis (辨證) indicated that the studies on wind-fire pattern (風火證) were highest. Yougeun-bang (柔筋方) in prescription and Paeoniae Radix Alba (白芍藥) in medicinal herbs were most used. This finding could be widely utilized in future clinical practice and form the basis for the development of clinical practice guidelines in advance. |
국문초록 | |
Language | 한국어 |
첨부파일 |