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근거중심한의약 DB

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Title

무릎 골관절염의 봉독 약침 치료에 대한 체계적 문헌 고찰

Authors

구지향, 김은석, 박양춘, 정인철, 이은정

Journal

한방재활의학과학회지.

Year

2017

Vol (Issue)

27(3)

Page

47-60.

doi

10.18325/jkmr.2017.27.3.47

PMID

Url

http://www.ndsl.kr/ndsl/search/detail/article/articleSearchResultDetail.do?cn=JAKO201722647666908

MeSH

Keywords

Knee Osteoarthritis; Bee Venom; Systematic review; Meta-analysis

한글 키워드

무릎 골관절염; 봉독; 체계적 문헌고찰; 메타 분석

KMCRIC
Summary & Commentary

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Korean Study

Y

Abstract

Objectives: The aim of this research is to assess the effects of bee venom acupuncture for knee osteoarthritis. Methods: For a systematic review, we constructed a key question as the effect of bee venom acupuncture for knee osteoarthritis and selected RCTs and nRCTs. We searched the following 15 databases without a language restriction: Pubmed, EMBASE, Cochrane CENTRAL (CENTRAL), CINAHL, AMED, seven Korean medical databases (KoreaMed, Kmbase, KISS, NDSL, KISTI, Koreantk, OASIS) and three Chinese databases including CNKI, Wanfang and VIP database. Results: A total of 300 potentially relevant studies were identified; only 13 studies were selected for systematic review. Almost studies showed that bee venom acupuncture has significant effect on knee osteoarthritis. 5 studies comparing bee venom acupuncture with acupuncture were included in the meta-analysis. The effect size of standardized mean difference (SMD) was analyzed as 'small effect' with 0.47 (95% CI: 0.10~0.83, Z=2.49, p=0.01). Conclusions: The research showed that bee venom acupuncture can significantly reduce pain, stiffness and improve the quality of life of patients with knee osteoarthritis. However, most of the studies included in the analysis were evaluated as methodologically high risk of bias. This suggests that there is limitation applying this study. In the future, more Randomized Controlled trial should be actively conducted.

국문초록

Language

한국어

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