KMCRIC

기능성 자궁출혈에 대한 한약치료 : 체계적 문헌 고찰

박어진, 조희근, 최지현

대한한방부인과학회지.

2018

31(4)

110-27.

10.15204/jkobgy.2018.31.4.110

http://www.ndsl.kr/ndsl/search/detail/article/articleSearchResultDetail.do?cn=JAKO201836263119431

Dysfunctional Uterine Bleeding (DUB); Herbal Medicine; Chinese Herbal Medicine (CHM); Randomized Controlled Trial (RCT)

기능성 자궁 출혈; 한약; 중약학; 무작위배정 비교 임상시험

KMCRIC 비평 보기 +

Y

Objectives: To evaluate the effectiveness and safety of traditional herbal medicine (THM) in the treatment of dysfunctional uterine bleeding (DUB) versus conventional western medicine.

Methods: Randomized Controlled Trials (RCTs) comparing THM vs. conventional western medicine for DUB, were obtained from PubMed, Cochrane Library, Embase, CNKI, RISS, NDSL, KISS and OASIS. The risk of bias was assessed by using Cochrane's risk of bias tool.

Results: 16 RCTs with 1,659 patients were identified and reviewed. 10 RCTs reported THM was statistically effective than control group in effective rate. Also recurrent rate was estimated in 6 RCTs and was lower than control group. 7 studies observed adverse events (AEs) and severe AEs were not reported.

Conclusions: Despite several limitations, this review suggested that THM was safe and effective in the treatment of DUB. THM may also decrease the recurrence rate. However, this could not be proven conclusively. To ensure evidence-based clinical practice, more sternly designed trials are warranted.

한국어

S201811999.pdf