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| Title | 만성피로증후군에 대한 소요산(逍遙散)과 그 변방(變方)의 효과 : 메타분석을 통한 체계적인 문헌고찰. |
|---|---|
| Authors | 김준열, 송정윤, 남동현. |
| Journal | 동의생리병리학회지. |
| Year | 2020 |
| Vol (Issue) | 제 34권 제 3호 |
| Page | 117-25. |
| doi | |
| PMID | |
| Url | |
| MeSH | |
| Keywords | Soyo-san (Xiaoyao-san), Chronic fatigue syndrome, Meta-analysis, Systematic review |
| 한글 키워드 | |
| KMCRIC summary and commentary | 없음 |
| Korean Study | Y |
| Abstract | The purpose of this review is to confirm whether Soyo-san (Xiaoyao-san) and its modifications is effective on alleviating clinical symptoms in chronic fatigue syndrome (CFS) patients. We collected clinical trials (randomized controlled trial, quasi-randomized controlled trial, controlled clinical trial) to investigate the effects of Soyo-san and its modifications on general symptoms, fatigue, depression and anxiety in CFS patients. The databases used for data retrieval were Pubmed, Central Cochrane, Embase, CNKI, CQVIP, Wanfang, CiNii, OASIS, RISS, and Koreamed. We performed selection/exclusion process from the found studies to conform with prespecified criteria, and assessed the final included trials according to the Cochrane risk of bias tool. The included studies were classified based on the interventions in experimental and control group. Eight randomized controlled trials and one controlled clinical trial (total 921 participants) were eligible and their results were synthesized in the meta analysis. The synthesis showed a considerable effect of Soyo-san and its modifications on improvement of general symptoms (relative risk 0.27 [95% CI 0.19 to 0.39], Z=7.03, P<0.00001; I2=0%) and fatigue severity (SMD –1.20 [95% CI –1.46 to –0.93], Z=8.78, P<0.00001; I2=52%) in CFS patients, while Effect on depression and anxiety were inconclusive. We found that Soyo-san and its modifications were effective for improvement of general symptoms and fatigue severity in CFS post-treatment. |
| 국문초록 | |
| Language | 한국어 |
| 첨부파일 |