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한의약융합데이터센터


생약 up-to-date

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복령   茯苓
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일반정보
일반명 Poria, indian bread, tuckahoe
라틴명 Poria Sclerotium
이명 복도(茯菟), 복령(伏苓), 운령(雲苓), 복면(茯免), 송령(松苓)
학명 Poria cocos Wolf (복령)
기원 복령 Poria cocos Wolf (구멍장이버섯과 Polyporaceae)의 균핵
약성/귀경 달고 담담하며(甘淡) 평이하다(平). 심(心), 비(脾), 폐경(肺經)에 작용한다.
효능 이수삼습(利水滲濕), 건비(健脾), 안신(安神) 이수삼습(利水滲濕): a therapeutic method to treat internal retention of dampness by using diuretics 건비(健脾): a therapeutic method of invigorating the transporting and transforming functions of the spleen 안신(安神): a general term for tranquilizing measures
성분정보
구분 계열 성분
주요 triterpenoid pachymic acid
주요 triterpenoid eburicoic acid
주요 triterpenoid tumulosic acid
주요 triterpenoid dehydroeburicoic acid
신규 terpenoid 16α-hydroxy-3-oxo-24-methyllanosta-5,7,9(11),24(31)-tetraen-21-oic acid (1), 3β,16α,29-trihydroxy-24-methyllanosta-7,9(11),24(31)-trien-21-oic acid (2), 3β,16α,30-trihydroxy-24-methyllanosta-7,9(11),24(31)-trien-21-oic acid (3), 3β-acetoxy-16α,24β-dihydroxylanosta-7,9(11),25-trien-21-oic acid (4), 3β,16α-dihydroxy-7-oxo-24-methyllanosta-8,24(31)-dien-21-oic acid (5), 3α,16α-dihydroxy-7-oxo-24-methyllanosta-8,24(31)-dien-21-oic acid (6)
신규 terpenoid 3-(2-hydroxyacetoxy)-5α, 8α-peroxydehydrotumulosic acid
신규 terpenoid 29-hydroxydehydrotumulosic acid (1), 29-hydroxydehydropachymic acid (2)
신규 terpenoid 29-hydroxypolyporenic acid C
신규 terpenoid poriacosones A (8), B (9)
신규 terpenoid 29-hydroxypolyporenic acid C (4), 25-hydroxypachymic acid (5)
신규 terpenoid 15alpha-hydroxydehydrotumulosic acid (5),16alpha,25-dihydroxydehydroeburicoic acid (9), 5alpha,8alpha-peroxydehydrotumulosic acid (10), 25-hydroxyporicoic acid H (11), 16-deoxyporicoic acid B (12), poricoic acid CM (16)

*계열/성분을 클릭하면 구조 및 상세정보를 볼 수 있습니다.



주요성분 (4)
계열 성분 구조 링크 효능
triterpenoid pachymic acid 항당뇨, 이뇨
triterpenoid eburicoic acid 항당뇨, 이뇨
triterpenoid tumulosic acid 항당뇨, 이뇨
triterpenoid dehydroeburicoic acid 항당뇨, 이뇨

신규성분 (7)
계열 성분 구조 서지사항
terpenoid 16α-hydroxy-3-oxo-24-methyllanosta-5,7,9(11),24(31)-tetraen-21-oic acid (1), 3β,16α,29-trihydroxy-24-methyllanosta-7,9(11),24(31)-trien-21-oic acid (2), 3β,16α,30-trihydroxy-24-methyllanosta-7,9(11),24(31)-trien-21-oic acid (3), 3β-acetoxy-16α,24β-dihydroxylanosta-7,9(11),25-trien-21-oic acid (4), 3β,16α-dihydroxy-7-oxo-24-methyllanosta-8,24(31)-dien-21-oic acid (5), 3α,16α-dihydroxy-7-oxo-24-methyllanosta-8,24(31)-dien-21-oic acid (6) Lai KH, Lu MC, Du YC, El-Shazly M, Wu TY, Hsu YM, Henz A, Yang JC, Backlund A, Chang FR, Wu YC. Cytotoxic Lanostanoids from Poria cocos. J Nat Prod. 2016 Nov 23;79(11):2805-2813. PubMed
terpenoid 3-(2-hydroxyacetoxy)-5α, 8α-peroxydehydrotumulosic acid Li S, Wang Z, Gu R, Zhao Y, Huang W, Wang Z, Xiao W. A new epidioxy-tetracyclic triterpenoid from Poria cocos Wolf. Nat Prod Res. 2016 Aug;30(15):1712-7. PubMed
terpenoid 29-hydroxydehydrotumulosic acid (1), 29-hydroxydehydropachymic acid (2) Cai TG, Cai Y. Triterpenes from the fungus Poria cocos and their inhibitory activity on nitric oxide production in mouse macrophages via blockade of activating protein-1 pathway. Chem Biodivers. 2011 Nov;8(11):2135-43. PubMed
terpenoid 29-hydroxypolyporenic acid C Zhou L, Zhang Y, Gapter LA, Ling H, Agarwal R, Ng KY. Cytotoxic and anti-oxidant activities of lanostane-type triterpenes isolated from Poria cocos. Chem Pharm Bull (Tokyo). 2008 Oct;56(10):1459-62. PubMed
terpenoid poriacosones A (8), B (9) Zheng Y, Yang XW. Poriacosones A and B: two new lanostane triterpenoids from Poria cocos. J Asian Nat Prod Res. 2008 Jul-Aug;10(7-8):645-51. PubMed
terpenoid 29-hydroxypolyporenic acid C (4), 25-hydroxypachymic acid (5) Zheng Y, Yang XW. Two new lanostane triterpenoids from Poria cocos. J Asian Nat Prod Res. 2008 Mar-Apr;10(3-4):323-8. PubMed
terpenoid 15alpha-hydroxydehydrotumulosic acid (5),16alpha,25-dihydroxydehydroeburicoic acid (9), 5alpha,8alpha-peroxydehydrotumulosic acid (10), 25-hydroxyporicoic acid H (11), 16-deoxyporicoic acid B (12), poricoic acid CM (16) Akihisa T, Nakamura Y, Tokuda H, Uchiyama E, Suzuki T, Kimura Y, Uchikura K, Nishino H. Triterpene acids from Poria cocos and their anti-tumor-promoting effects. J Nat Prod. 2007 Jun;70(6):948-53. PubMed
약리정보

* 질병 분류 별 논문 수


질병 분류 임상 시험
human
동물 실험
in vivo
세포 및 시험관 실험
in vitro
total
(건)
종양(II) 0 9 11 20
혈액 및 혈액 생성 기관 질병으로 면역 체계와 관련된 병(III) 1 2 3 6
내분비선 영양 및 순환계(IV) 0 0 3 3
신경 계통의 질병(VI) 0 2 3 5
순환 계통의 질병(IX) 0 2 1 3
소화 계통의 질병(XI) 0 1 0 1
피부와 피하 조직의 질병(XII) 1 0 0 1
생식, 배설 계통의 질병(XIV) 0 5 2 7
상처, 중독과 외부 원인에 의한 것들(XIX) 0 1 2 3
기타(XXIV) 0 3 6 9
합계 2 25 31 58

*숫자를 클릭하면 약리작용 상세정보를 볼 수 있습니다.

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