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일반정보
| 일반명 | Gardenia fruit, cape jasmine fruit |
|---|---|
| 라틴명 | Gardeniae Fructus |
| 이명 | 목단(木丹), 선지(鮮支), 치자(巵子), 소치자(小巵子), 산치자(山梔子), 황치자(黃梔子) |
| 학명 | Gardenia jasminoides Ellis (치자나무) |
| 기원 | 치자나무 Gardenia jasminoides Ellis (꼭두서니과 Rubiaceae)의 잘 익은 열매 |
| 약성/귀경 | 쓰고(苦) 차고(寒) 독이 없다(無毒). 심(心)과 간(肝)과 폐(肺)와 위(胃)와 삼초경(三焦經)에 작용한다. |
| 효능 | 사화제번(瀉火除煩), 청열이습(淸熱利濕), 양혈해독(凉血解毒) 사화(瀉火): a therapeutic method of removing pathogenic fire by using bitter-cold medicinals 청열양혈; 양혈(淸熱凉血; 凉血): a therapeutic method of using heat-clearing and blood-cooling medicinals to treat blood heat pattern/syndrome 해독(解毒): (1) measure to lessen the virulence of pathogens; (2) a method of neutralizing the toxic property of poisons |
성분정보
*계열/성분을 클릭하면 구조 및 상세정보를 볼 수 있습니다.
일반정보
| 일반명 | Gardenia fruit, cape jasmine fruit |
|---|---|
| 라틴명 | Gardeniae Fructus |
| 이명 | 목단(木丹), 선지(鮮支), 치자(巵子), 소치자(小巵子), 산치자(山梔子), 황치자(黃梔子) |
| 학명 | Gardenia jasminoides Ellis (치자나무) |
| 기원 | 치자나무 Gardenia jasminoides Ellis (꼭두서니과 Rubiaceae)의 잘 익은 열매 |
| 약성/귀경 | 쓰고(苦) 차고(寒) 독이 없다(無毒). 심(心)과 간(肝)과 폐(肺)와 위(胃)와 삼초경(三焦經)에 작용한다. |
| 효능 | 사화제번(瀉火除煩), 청열이습(淸熱利濕), 양혈해독(凉血解毒) 사화(瀉火): a therapeutic method of removing pathogenic fire by using bitter-cold medicinals 청열양혈; 양혈(淸熱凉血; 凉血): a therapeutic method of using heat-clearing and blood-cooling medicinals to treat blood heat pattern/syndrome 해독(解毒): (1) measure to lessen the virulence of pathogens; (2) a method of neutralizing the toxic property of poisons |
| 관련링크명 | 구분 | URL | 바로가기 |
|---|---|---|---|
| 식약처 생약종합정보시스템 | www.nifds.go.kr/nhmi/hbdc/ofcmhbdc/view.do?selectedDmstcOfcmNo=499&selectedMdntfNo=964 | 바로가기+ | |
| 한국전통지식포탈 | 치자A | www.koreantk.com/ktkp2014/medicine/medicine-view.view?medCd=M0003881 | 바로가기+ |
| 한국전통지식포탈 | 치자B | www.koreantk.com/ktkp2014/medicine/medicine-view.view?medCd=M0003883 | 바로가기+ |
주요성분 (5)
| 계열 | 성분 | 구조 | 링크 | 효능 |
|---|---|---|---|---|
| iridoid | genipin |
|
|
이담, 간보호, 항염 |
| iridoid | geniposide |
|
|
이담, 간보호, 항염 |
| iridoid | gardenoside |
|
|
이담, 간보호, 항염 |
| etc | crocin |
|
|
항염, 항산화 |
| etc | crocetin |
|
|
항염, 항산화 |
신규성분 (14)
| 계열 | 성분 | 구조 | 서지사항 |
|---|---|---|---|
| flavonoid | quercetin-3-O-[2-O-trans-caffeoyl-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside] (1), quercetin-3-O-[2-O-trans-caffeoyl-β-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside] (2) |
|
Yu S, Fu S, Liu B, Zhang Y, Zhou G. Two new quercetin glycoside derivatives from the fruits of Gardenia jasminoides var. radicans. Nat Prod Res. 2015;29(14):1336-41. PubMed |
| triterpene | 3α,16β,23,24-tetrahydroxy-28-nor-ursane-12,17,19,21-tetraen |
|
Qin FM, Liu BL, Zhang Y, Zhou GX. A new triterpenoid from the fruits of Gardenia jasminoides var. radicans Makino. Nat Prod Res. 2015;29(7):633-7. PubMed |
| phenolic | threo-2-(4-hydroxy-3,5-dimethoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-3-ethoxypropan-1-ol |
|
Qin FM, Meng LJ, Zou HL, Zhou GX. Three new iridoid glycosides from the fruit of gardenia jasminoides var. radicans. Chem Pharm Bull (Tokyo). 2013;61(10):1071-4. PubMed |
| iridoid | 6''-O-trans-feruloylgenipin gentiobioside (1), 2'-O-trans-caffeoylgardoside (2), jasmigeniposide A (3), jasmigeniposide B (4) |
|
Li HB, Yu Y, Wang ZZ, Dai Y, Gao H, Xiao W, Yao XS. Iridoid and bis-iridoid glucosides from the fruit of Gardenia jasminoides. Fitoterapia. 2013 Jul;88:7-11. PubMed |
| iridoid | 6''-O-trans-caffeoylgenipin gentiobioside (1), genipin 1-O-β-D-apiofuranosyl (1→6)-β-D-glucopyranoside (2), genipin 1-O-α-D-xylopyranosyl (1→6)-β-D-glucopyranoside (3) |
|
Peng K, Yang L, Zhao S, Chen L, Zhao F, Qiu F. Chemical constituents from the fruit of Gardenia jasminoides and their inhibitory effects on nitric oxide production. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1127-31. PubMed |
| monoterpene | jasminoside R (4), jasminoside S (5), jasminoside T (6) |
|
Peng K, Yang L, Zhao S, Chen L, Zhao F, Qiu F. Chemical constituents from the fruit of Gardenia jasminoides and their inhibitory effects on nitric oxide production. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1127-31. PubMed |
| lignan | (+)-(7S,8R,8'R)-lyoniresinol 9-O-β-D-(6''-O-trans-sinapoyl)glucopyranoside |
|
Yu Y, Feng XL, Gao H, Xie ZL, Dai Y, Huang XJ, Kurihara H, Ye WC, Zhong Y, Yao XS. Chemical constituents from the fruits of Gardenia jasminoides Ellis. Fitoterapia. 2012 Apr;83(3):563-7. PubMed |
| iridoid | 10-O-trans-sinapoylgeniposide |
|
Yu Y, Feng XL, Gao H, Xie ZL, Dai Y, Huang XJ, Kurihara H, Ye WC, Zhong Y, Yao XS. Chemical constituents from the fruits of Gardenia jasminoides Ellis. Fitoterapia. 2012 Apr;83(3):563-7. PubMed |
| sesquiterpene | (1R,7R,10S)-11-O-β-D-glucopyranosyl-4-guaien-3-one (1), (1R,7R,10S)-7-hydroxy-11-O-β-Dglucopyranosyl-4-guaien-3-one (2) |
|
Yu Y, Gao H, Dai Y, Xiao GK, Zhu HJ, Yao XS. Guaiane-type sesquiterpenoid glucosides from Gardenia jasminoides Ellis. Magn Reson Chem. 2011 May;49(5):258-61. PubMed |
| iridoid | 6''-O-trans-sinapoylgenipin gentiobioside (1), 6''-O-trans-p-coumaroylgenipin gentiobioside (2), 6''-O-trans-cinnamoylgenipin gentiobioside (3), 6'-O-trans-p-coumaroylgeniposide (4), 6'-O-trans-p-coumaroylgeniposidic acid (5), 10-O-succinoylgeniposide (6), 6'-O-acetylgeniposide (7) |
|
Yu Y, Xie ZL, Gao H, Ma WW, Dai Y, Wang Y, Zhong Y, Yao XS. Bioactive iridoid glucosides from the fruit of Gardenia jasminoides. J Nat Prod. 2009 Aug;72(8):1459-64. PubMed |
| monoterpene | 11-(6-O-trans-sinapoylglucopyranosyl)gardendiol (8), 10-(6-O-trans-sinapoylglucopyranosyl)gardendiol (9) |
|
Yu Y, Xie ZL, Gao H, Ma WW, Dai Y, Wang Y, Zhong Y, Yao XS. Bioactive iridoid glucosides from the fruit of Gardenia jasminoides. J Nat Prod. 2009 Aug;72(8):1459-64. PubMed |
| monoterpene | jasminodiol (1), jasminoside H (6), 6'-O-sinapoyljasminoside A (7), 6'-O-sinapoyljasminoside C (8), jasminoside I (9) |
|
Chen QC, Youn U, Min BS, Bae K. Pyronane monoterpenoids from the fruit of Gardenia jasminoides. J Nat Prod. 2008 Jun;71(6):995-9. PubMed |
| iridoid | new iridoid natural product |
|
Ragasa CY, Pimenta LE, Rideout JA. Iridoids from Gardenia jasminoides. Nat Prod Res. 2007 Oct;21(12):1078-84. PubMed |
| flavonoid | quercetin-3-O-[2-O-trans-caffeoyl-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside] (1), quercetin-3-O-[2-O-trans-caffeoyl-β-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside] (2) |
|
Kim HJ, Kim EJ, Seo SH, Shin CG, Jin C, Lee YS. Vanillic acid glycoside and quinic acid derivatives from Gardeniae Fructus. J Nat Prod. 2006 Apr;69(4):600-3. PubMed |
약리정보
* 질병 분류 별 논문 수
| 질병 분류 | 임상 시험 human |
동물 실험 in vivo |
세포 및 시험관 실험 in vitro |
total (건) |
|---|---|---|---|---|
| 전염병 또는 기생충병(I) | 0 | 3 | 1 | 4 |
| 종양(II) | 0 | 0 | 5 | 5 |
| 혈액 및 혈액 생성 기관 질병으로 면역 체계와 관련된 병(III) | 0 | 0 | 1 | 1 |
| 내분비선 영양 및 순환계(IV) | 0 | 3 | 0 | 3 |
| 정신적, 행동적 장애(V) | 1 | 3 | 0 | 4 |
| 신경 계통의 질병(VI) | 0 | 1 | 4 | 5 |
| 눈과 그에 딸린 기관의 질병(VII) | 0 | 1 | 0 | 1 |
| 순환 계통의 질병(IX) | 0 | 2 | 2 | 4 |
| 호흡기 계통의 질병(X) | 0 | 1 | 0 | 1 |
| 소화 계통의 질병(XI) | 0 | 8 | 0 | 8 |
| 피부와 피하 조직의 질병(XII) | 0 | 1 | 3 | 4 |
| 근육과 연결 조직의 질병(XIII) | 0 | 3 | 0 | 3 |
| 항산화 또는 항염증(XXIII) | 0 | 2 | 3 | 5 |
| 합계 | 1 | 28 | 19 | 48 |
*숫자를 클릭하면 약리작용 상세정보를 볼 수 있습니다.