KMCRIC

The intake ratio of omega-3 to omega-6 might play a role in the effects of these fatty acids. Based on animal research, the ratio of alpha-linolenic acid to linoleic acid may be useful to determine the effects of alpha-linolenic acid on cholesterol and arachidonic acid [​52​]. This ratio has been examined and shown to affect biochemical outcomes in various animal studies [​53​]. Also, supplementation with omega-3 fatty acids has been shown to reduce omega-6 status (blood, muscle) in human, animal, and in vitro research [​16​;​43​;​54​;​55​;​56​;​57​;​58​;​59​;​60​;​61​;​62​;​63​;​64​;​65​;​66​;​67​;​68​;​69​;​70​;​71​;​72​]; however, when omega-6 was increased in addition to omega-3, omega-6 levels did not decrease, in human research [​73​]. Altering the ratio of omega-3 to omega-6 fatty acids may alter neurogenesis by influencing membrane proteins, cytokines, or neurotrophins [​74​]. Based on reviews, the appropriate combination of omega-3 and omega-6 fatty acids may show additional benefits in the form of protection from depression, schizophrenia, and Alzheimer's disease [​75​;​76​], as well as ADHD [​77​]. In children with developmental coordination disorder, a product containing both omega-6 and omega-3 fatty acids resulted in improvements in reading, spelling, and behavior [160]. In human research, supplementation with 2g of eicosapentaenoic acid (omega-3) daily increased red cell membrane levels of arachidonic acid (omega-6) [​88​]. This is not a common finding.

... [​74​]. 연구들에 따르면, 오메가-3와 오메가-6의 적절한 조합은 주의력 결핍 행동 장애를 포함한 우울증, 조현병, 알츠하이머 병의 예방에 추가적인 유익함을 나타낼 수 있다 [​75​;​76​]. 발달 협응 장애 아동에게서, 오메가-6와...

Theoretically, concurrent use of caffeine and nicotine may increase the risk of psychiatric and cardiovascular adverse effects, as both agents are known stimulants. In humans, caffeine enhanced the thermogenic response observed following ingestion of nicotine gum [​217​]. None of the nicotine-caffeine combinations changed the respiratory quotient compared to placebo, indicating that glucose and fat oxidation rates were increased to a similar extent. Caffeine showed additive effects on cardiovascular parameters with nicotine [​151​]. In humans, however, infrequent acute caffeine administration attenuated the "high" of nicotine [​144​]. Concomitant consumption of caffeine and cigarettes during pregnancy placed the developing fetus at higher risk for diminished growth [​218​]. In humans, patients with schizophrenia who smoked had higher serum caffeine levels [768]. In some young women, attention was improved following nicotine use in those consuming the greatest amounts of caffeine [​219​].

... 발달중인 태아를 감소된 성장에 대한 더 높은 위험에 처하게 하였다 [​218​]. 임상 연구에서, 흡연을 하는 조현병 환자는 더 높은 혈청 카페인 수치를 가졌다 [768]. 일부 젊은 여성의 경우, 많은 양의 카페인을 섭취하는...

Prunella vulgaris could be useful for treating schizophrenia because EEPV ameliorates prepulse inhibition disruption and attention deficits induced by dizocilpine.

하고초 에탄올 추출물은 dizocilpine에 의한 주의력 결핍과 전펄스 억제 파괴를 개선하여 조현병 치료에 도움이 됨.

Gastrodia elata Bl significantly attenuated PCP-induced abnormal behaviors including decreased social interaction time and recognition memory. Furthermore, GE-mediated effects were counteracted by WAY 100635, a 5-HT(1A) receptor antagonist.

천마 (Gastrodia Elata bl)는 phencyclidine 유도 조현병 유사 정신증 모델에서 사회적 상호작용 시간과 인식 기억 감소와 같은 비정상적 행동을 완화함. 또한, 이 효과는 5-HT(1A) 수용체 길항물질인 WAY 100635와 비견됨.