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근거중심한의약 DB

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Title

Clinical efficacy of herbal extract cream on the skin hydration, elasticity, thickness, and dermis density for aged skin: A randomized controlled double-blind study.

Authors

Roh SS, Choi I, Kim HM, Lee MS, Jin MH, Kim BH, Hwang SJ, Kim MH.

Journal

J Cosmet Dermatol.

Year

2019

Vol (Issue)

Page

doi

10.1111/jir.12602.

PMID

30636339

Url

http://www.ncbi.nlm.nih.gov/pubmed/30636339

MeSH

Keywords

Asian; Korean; Sang-Hyul-Yun-Boo-Em; aging; herbal medicine; traditional medicine

한글 키워드

KMCRIC
Summary & Commentary

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Korean Study

Y

Abstract

BACKGROUND:
Traditional medicine herbal prescriptions used for the treatment of skin disease have been developed into cosmetics. Sang-Hyul-Yun-Boo-Em (SHYBE) is a mixed herbal formula prescribed for patients with yin or blood deficiency patterns of skin disease. A previous study reported that SHYBE exercises anti-allergic and anti-inflammatory effects. To date, no study has reported the efficacy of cosmetics containing the SHYBE extract.

AIMS:
To observe the efficacy of SHYBE extract cream on hydration, elasticity, thickness, and dermis density in aged skin.

METHODS:
This was a double-blind randomized placebo-controlled parallel-group trial. The trial consisted of an 8-week topical application of the test or placebo products with two visits at 4-week intervals. A total of 46 healthy Korean females, aged 40-59, were enrolled in this study. Objective skin assessments for hydration, elasticity, thickness and dermis density, self-assessment, and safety assessment were conducted.

RESULTS:
Sang-Hyul-Yun-Boo-Em extract cream improved skin hydration, elasticity, and dermal density in Asian middle-aged females compared with placebo cream, which excluded SHYBE extract and contained other cosmetic materials.

CONCLUSIONS:
Sang-Hyul-Yun-Boo-Em extract cream showed anti-aging properties in middle-aged women. It could be recommended for aging skin with dryness, and loss of elasticity and density.

© 2019 Wiley Periodicals, Inc.

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