| Title |
Paeoniae Radix-containing herbal medicine for patients with restless legs syndrome: A systematic review and meta-analysis. |
| Authors |
Kwon S, Jin C, Cho SY, Park SU, Jung WS, Moon SK, Park JM, Ko CN, Cho KH. |
| Journal |
Complement Ther Clin Pract. |
| Year |
2019 |
| Vol (Issue) |
35 |
| Page |
329-41. |
| doi |
10.1016/j.ctcp.2019.03.015. |
| PMID |
31003678 |
| Url |
http://www.ncbi.nlm.nih.gov/pubmed/31003678 |
| MeSH |
Adult
Aged
Aged, 80 and over
Female
Herbal Medicine*
Humans
Male
Middle Aged
Paeonia/chemistry*
Phytotherapy/methods*
Plants, Medicinal/chemistry*
Restless Legs Syndrome/drug therapy* |
| Keywords |
Herbal medicine; Meta-analysis; Paeoniae Radix; Restless legs syndrome; Systematic review |
| 한글 키워드 |
|
KMCRIC
Summary & Commentary |
KMCRIC 비평 보기 + |
| Korean Study |
Y |
| Abstract |
BACKGROUND AND PURPOSE:
Paeoniae Radix has been used for legs discomfort such as restless legs syndrome. The aim of this review is to evaluate efficacy and safety of Paeoniae Radix-containing herbal medicine on restless legs syndrome.
METHODS:
Literature search was conducted on PubMed, Scopus, CENTRAL, CiNii, KTKP, OASIS, and CNKI for randomized controlled trials that evaluated the effects of Paeoniae Radix-containing herbal medicines on restless legs syndrome.
RESULTS:
Twelve studies (n = 639) were included. The overall methodological quality was low. In the herbal group, meta-analysis indicated statistically significant improvements in the total effective rate, the restless legs syndrome rating scale and the Pittsburgh Sleep Quality Index as compared with those in the non-herbal group. Herbal treatments were found to be relatively safe.
CONCLUSION:
Paeoniae Radix-containing herbal medicines might promote improvements in restless legs syndrome. However, we are unable to draw concrete conclusions owing to limitations of the included studies.
Copyright © 2019 Elsevier Ltd. All rights reserved. |
| 국문초록 |
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| Language |
영어 |
| 첨부파일 |
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