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일반정보
일반명 Cassia seed
라틴명 Cassiae Semen
이명 초결명(草決明), 양명(羊明), 양각(羊角), 마제결명(馬蹄決明)
학명 Cassia tora Linné (결명차), Cassia obtusifolia Linné (결명)
기원 결명차 Cassia tora Linne 또는 결명 (決明) Cassia obtusifolia Linne (콩과 Leguminosae)의 잘 익은 씨
약성/귀경 달고(甘) 쓰고(苦) 짜며(鹹) 약간 차다(微寒). 간(肝)과 대장경(大腸經)에 작용한다.
효능 청간명목(淸肝明目), 평간잠양(平肝潛陽), 윤장통변(潤腸通便) 청간(淸肝): a therapeutic method of clearing the liver heat or fire 명목(明目): any therapeutic method that can ameliorate impairment of vision 평간잠양(平肝潛陽): a therapeutic method to treat ascendant hyperactivity of liver yang by using yin blood nourishing medicinals and heavy mineral and shell medicinals 윤장(潤腸): a therapeutic method for constipation due to intestinal dryness by using moistening medicinals 통변(通便): therapeutic method for relieving constipation
성분정보
구분 계열 성분
주요 anthraquinone chrysophanol
주요 anthraquinone physcion
주요 anthraquinone emodin
주요 anthraquinone obtusifolin
주요 anthraquinone obtusin
신규 anthraquinone 8-hydroxy-1,7-dimethoxy-3-methylanthracene-9,10-dione-2-O-β-d-glucoside
신규 anthraquinone 6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone (1), 2-O-b-D-Glucopyranosyloxy-1,7,8-trimethoxy-3-Methylanthraquinone (2), 2-O-b-D-Glucopyranosyloxy-8hydroxy-1,7-dimethoxy-3-methylanthraquinone (3), 6-O-b-D-Glucopyranosyloxy-8-hydroxy-1,2,7-trimethoxy-3-methylanthraquinone (4), 6-O-b-D-Glucopyranosyloxy-1-hydroxy-2,8-dimethoxy-3-methylanthraquinone (5)
신규 anthraquinone 13-methyl-2,8-dihydroxy-1,7-dimethoxy anthraquinone (7-methoxyobtusifolin)
신규 anthraquinone 2-benzyl-4,6-dihydroxy benzoic acid-6-O-[2,6-O-diacetyl]-D-glucopyranoside (1), 2-benzyl-4,6-dihydroxy benzoic acid-6-O-[3,6-O-diacetyl]-D-glucopyranoside (2), 2-benzyl-4, 6-dihydroxy benzoic acid-6-O-[4,6-O-diacetyl]-D-glucopyranoside (3)
신규 anthraquinone obtusifoline-2-O-β-d-2, 6-di-O-acetylglucopyranoside (1), obtusifoline-2-O-β-d-3, 6-di-O-acetylglucopyranoside (2), obtusifoline-2-O-β-d-4, 6-di-O-acetylglucopyranoside (3)
신규 anthraquinone benzyl-4,6-dihydroxy benzoic acid (1), 2-benzyl-4,6-dihydroxy benzoic acid-6-O-beta-D-glucopyranoside (2), 2-benzyl-4,6-dihydroxy benzoic acid-4-O-beta-D-glucopyranoside (3)

*계열/성분을 클릭하면 구조 및 상세정보를 볼 수 있습니다.


일반정보
일반명 Cassia seed
라틴명 Cassiae Semen
이명 초결명(草決明), 양명(羊明), 양각(羊角), 마제결명(馬蹄決明)
학명 Cassia tora Linné (결명차), Cassia obtusifolia Linné (결명)
기원 결명차 Cassia tora Linne 또는 결명 (決明) Cassia obtusifolia Linne (콩과 Leguminosae)의 잘 익은 씨
약성/귀경 달고(甘) 쓰고(苦) 짜며(鹹) 약간 차다(微寒). 간(肝)과 대장경(大腸經)에 작용한다.
효능 청간명목(淸肝明目), 평간잠양(平肝潛陽), 윤장통변(潤腸通便) 청간(淸肝): a therapeutic method of clearing the liver heat or fire 명목(明目): any therapeutic method that can ameliorate impairment of vision 평간잠양(平肝潛陽): a therapeutic method to treat ascendant hyperactivity of liver yang by using yin blood nourishing medicinals and heavy mineral and shell medicinals 윤장(潤腸): a therapeutic method for constipation due to intestinal dryness by using moistening medicinals 통변(通便): therapeutic method for relieving constipation
관련링크명 구분 URL 바로가기
농촌진흥청 농업기술길잡이 www.nongsaro.go.kr/portal/ps/psb/psbx/cropEbookLst.ps?menuId=PS65290&stdPrdlstCode=IC&sStdPrdlstCode=IC0319ZZ# 바로가기+
한국전통지식포탈 결명자A www.koreantk.com/ktkp2014/medicine/medicine-view.view?medCd=M0000145 바로가기+
한국전통지식포탈 결명자B www.koreantk.com/ktkp2014/medicine/medicine-view.view?medCd=M0000146 바로가기+
식약처 생약종합정보시스템 결명 www.nifds.go.kr/nhmi/hbdc/ofcmhbdc/view.do?selectedDmstcOfcmNo=27&selectedMdntfNo=32 바로가기+
식약처 생약종합정보시스템 결명차 www.nifds.go.kr/nhmi/hbdc/ofcmhbdc/view.do?selectedDmstcOfcmNo=27&selectedMdntfNo=33 바로가기+
ALL (11) 주요성분(5) 신규성분(2005년 이후)(6)

주요성분 (5)
계열 성분 구조 링크 효능
anthraquinone chrysophanol 이뇨, 완하, 소염
anthraquinone physcion 이뇨, 완하, 소염
anthraquinone emodin 이뇨, 완하, 소염
anthraquinone obtusifolin 이뇨, 완하, 소염
anthraquinone obtusin 이뇨, 완하, 소염

신규성분 (6)
계열 성분 구조 서지사항
anthraquinone 8-hydroxy-1,7-dimethoxy-3-methylanthracene-9,10-dione-2-O-β-d-glucoside Shi BJ, Zhang WD, Jiang HF, Zhu YY, Chen L, Zha XM, Lu YY, Zhang WM. A new anthraquinone from seed of Cassia obtusifolia. Nat Prod Res. 2016;30(1):35-41. PubMed
anthraquinone 6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone (1), 2-O-b-D-Glucopyranosyloxy-1,7,8-trimethoxy-3-Methylanthraquinone (2), 2-O-b-D-Glucopyranosyloxy-8hydroxy-1,7-dimethoxy-3-methylanthraquinone (3), 6-O-b-D-Glucopyranosyloxy-8-hydroxy-1,2,7-trimethoxy-3-methylanthraquinone (4), 6-O-b-D-Glucopyranosyloxy-1-hydroxy-2,8-dimethoxy-3-methylanthraquinone (5) Xu YL, Tang LY, Zhou XD, Zhou GH, Wang ZJ. Five new anthraquinones from the seed of Cassia obtusifolia. Arch Pharm Res. 2015 Jun;38(6):1054-8. PubMed
anthraquinone 13-methyl-2,8-dihydroxy-1,7-dimethoxy anthraquinone (7-methoxyobtusifolin) Lee GY, Kim JH, Choi SK, Kim YH. Constituents of the seeds of Cassia tora with inhibitory activity on soluble expoxide hydrolease. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5097-101 PubMed
anthraquinone 2-benzyl-4,6-dihydroxy benzoic acid-6-O-[2,6-O-diacetyl]-D-glucopyranoside (1), 2-benzyl-4,6-dihydroxy benzoic acid-6-O-[3,6-O-diacetyl]-D-glucopyranoside (2), 2-benzyl-4, 6-dihydroxy benzoic acid-6-O-[4,6-O-diacetyl]-D-glucopyranoside (3) Wu X, Ruan J, Yang VC, Wu Z, Lou J, Duan H, Zhang J, Zhang Y, Guo D. Three new acetylated benzyl-beta-resorcylate glycosides from Cassia obtusifolia.Fitoterapia. 2012 Jan;83(1):166-9. PubMed
anthraquinone obtusifoline-2-O-β-d-2, 6-di-O-acetylglucopyranoside (1), obtusifoline-2-O-β-d-3, 6-di-O-acetylglucopyranoside (2), obtusifoline-2-O-β-d-4, 6-di-O-acetylglucopyranoside (3) Wu XH, Cai JJ, Ruan JL, Lou JS, Duan HQ, Zhang J, Cheng CR, Guo DA, Wu ZY, Zhang YW. Acetylated anthraquinone glycosides from Cassia obtusifolia. J Asian Nat Prod Res. 2011 Jun;13(6):486-91. PubMed
anthraquinone benzyl-4,6-dihydroxy benzoic acid (1), 2-benzyl-4,6-dihydroxy benzoic acid-6-O-beta-D-glucopyranoside (2), 2-benzyl-4,6-dihydroxy benzoic acid-4-O-beta-D-glucopyranoside (3) Wu XH, Ruan JL, Cheng CR, Wu ZY, Guan SH, Tao SJ, Xu PP, Guo DA. Benzyl-beta-resorcylates from Cassia obtusifolia. Fitoterapia. 2010 Sep;81(6):617-20. PubMed
약리정보

* 질병 분류 별 논문 수


질병 분류 임상 시험
human		 동물 실험
in vivo		 세포 및 시험관 실험
in vitro		 total
(건)
전염병 또는 기생충병(I) 0 0 3 3
종양(II) 0 3 3 6
혈액 및 혈액 생성 기관 질병으로 면역 체계와 관련된 병(III) 0 0 3 3
내분비선 영양 및 순환계(IV) 1 6 5 12
신경 계통의 질병(VI) 0 4 2 6
눈과 그에 딸린 기관의 질병(VII) 0 3 0 3
순환 계통의 질병(IX) 0 1 3 4
소화 계통의 질병(XI) 0 3 5 8
피부와 피하 조직의 질병(XII) 1 1 1 3
생식, 배설 계통의 질병(XIV) 0 1 2 3
항산화 또는 항염증(XXIII) 0 1 3 4
합계 2 23 30 55

*숫자를 클릭하면 약리작용 상세정보를 볼 수 있습니다.

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