KMCRIC

화면크기

한의약융합데이터센터

한의약융합데이터 콘텐츠 바로가기

생약 up-to-date

Home > 한의약융합데이터센터 > 생약 up-to-date

상지 桑枝

※ 생약 정보 공유 시 출처: KMCRIC 생약 up-to-date을 꼭 표기해 주세요.

※ 사진 정보 공유 시 출처: KIOM 본초감별도감을 꼭 표기해 주세요.

일반정보

일반명	Mulberry twig, 뽕나무가지
라틴명	Mori Ramulus
이명	눈상지(嫩桑枝), 상조(桑條)
학명	Morus alba Linné (뽕나무)
기원	뽕나무 Morus alba Linne 또는 기타 동속 근연식물 (뽕나무과 Moraceae)의 어린 가지
약성/귀경	쓰고(苦) 평하다(平). 간경(肝經)에 작용한다.
효능	거풍통락(祛風通絡), 이수퇴종(利水退腫) 거풍통락(祛風通絡): a therapeutic method to treat numbness, paralysis or muscle contracture due to wind-dampness impeding the collateral/network vessels 이수소종(利水消腫): a therapeutic method to treat edema by using diuretics

성분정보

구분	계열	성분
주요	flavonoid	morusin
주요	flavonoid	mulberrin
주요	flavonoid	kuwanon G
주요	stilbene	oxyresveratrol
주요	benzofuran	moracin M
신규	flavonoid	morusalbols A, B (1, 2)
신규	phenolic	10-oxomornigrol F (1), (7''R)-(-)-6-(7''-hydroxy-3'',8''-dimethyl-2'',8''-octadien-1''-yl)apigenin (2), ramumorin A (3), ramumorin B (4), (4S,7S,8R)-trihydroxyoctadeca-5Z-enoic acid (5)
신규	flavonoid	steppogenin-5'-C-β-D-glucopyranoside
신규	benzofuran	moracin O-3''-O-β-D-glucopyranoside, moracin O-3'-O-β-D-xylopyranoside, moracin P-2''-O-β-D-glucopyranoside, moracin P-3'-O-β-D-glucopyranoside, moracin P-3'-O-α-L-arabinopyranoside, moracin P-3'-O-[β-D-glucopyranosyl-(1→2)]-α-L-arabinopyranoside
신규	phenolic	2,4-dihydroxy-5-(4-hydroxybenzyl) benzoic acid, 2,4-dihydroxy-5-(3,4-dihydroxybenzyl) benzoic acid
신규	flavonoid	sanggenon U (1), sanggenon V (2), sanggenon W (3)
신규	flavonoid	soroceal B (1), sanggenol Q (7)
신규	benzofuran	(2''R)-(-)-moracin-O-5',3''-β-D-diglucopyranoside (1), (2''R)-(-)-moracin-P-5',2''-β-d-diglucopyranoside (2)
신규	phenolic	(2R,3S)-guibourtinidol-3-O-α-d-apiofuranosyl-(1→6)-O-β-D-glucopyranoside (1)
신규	flavonoid	(2S)-4'-hydroxy-7-methoxy-8-prenylflavan
신규	triterpenoid	lup-20(29)-en-3β-ol-27-oic acid (moruslupenoic acid A), lup-12, 20(29)-dien-3β-ol-26-oic acid (moruslupenoic acid B), lanst-5, 24-dien-3β-yl acetate (moruslanosteryl acetate)
신규	flavonoid	3'-geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone

*계열/성분을 클릭하면 구조 및 상세정보를 볼 수 있습니다.

일반정보

일반명	Mulberry twig, 뽕나무가지
라틴명	Mori Ramulus
이명	눈상지(嫩桑枝), 상조(桑條)
학명	Morus alba Linné (뽕나무)
기원	뽕나무 Morus alba Linne 또는 기타 동속 근연식물 (뽕나무과 Moraceae)의 어린 가지
약성/귀경	쓰고(苦) 평하다(平). 간경(肝經)에 작용한다.
효능	거풍통락(祛風通絡), 이수퇴종(利水退腫) 거풍통락(祛風通絡): a therapeutic method to treat numbness, paralysis or muscle contracture due to wind-dampness impeding the collateral/network vessels 이수소종(利水消腫): a therapeutic method to treat edema by using diuretics

관련링크명	구분	URL	바로가기
식약처 생약종합정보시스템		www.nifds.go.kr/nhmi/hbdc/ofcmhbdc/view.do?selectedDmstcOfcmNo=258&selectedMdntfNo=472	바로가기+
한국전통지식포탈		www.koreantk.com/ktkp2014/medicine/medicine-view.view?medCd=M0001855	바로가기+
농촌진흥청 농업기술길잡이	뽕나무오디	www.nongsaro.go.kr/portal/ps/psb/psbx/cropEbookLst.ps?menuId=PS65290&stdPrdlstCode=IN&sStdPrdlstCode=IN0142W1#	바로가기+

ALL (17) 주요성분(5) 신규성분(2005년 이후)(12)

주요성분 (5)

계열	성분	구조	링크	효능
flavonoid	morusin			이뇨, 소염, 항균
flavonoid	mulberrin			이뇨, 소염, 항균
flavonoid	kuwanon G			이뇨, 소염, 항균
stilbene	oxyresveratrol			이뇨, 소염, 항균
benzofuran	moracin M			이뇨, 소염, 항균

신규성분 (12)

계열	성분	구조	서지사항
flavonoid	morusalbols A, B (1, 2)		Gao L, Li YD, Zhu BK, Li ZY, Huang LB, Li XY, Wang F, Ren FC, Liao TG. Two new prenylflavonoids from Morus alba. J Asian Nat Prod Res. 2017 Jun 23:1-5. PubMed
phenolic	10-oxomornigrol F (1), (7''R)-(-)-6-(7''-hydroxy-3'',8''-dimethyl-2'',8''-octadien-1''-yl)apigenin (2), ramumorin A (3), ramumorin B (4), (4S,7S,8R)-trihydroxyoctadeca-5Z-enoic acid (5)		Tran HNK, Nguyen VT, Kim JA, Rho SS, Woo MH, Choi JS, Lee JH, Min BS. Anti-inflammatory activities of compounds from twigs of Morus alba. Fitoterapia. 2017 Jul;120:17-24. PubMed
flavonoid	steppogenin-5'-C-β-D-glucopyranoside		Zheng XK, Cao YG, Ke YY, Zhang YL, Li F, Gong JH, Zhao X, Kuang HX, Feng WS. Phenolic constituents from the root bark of Morus alba L. and their cardioprotective activity in vitro. Phytochemistry. 2017 Mar;135:128-134. PubMed
benzofuran	moracin O-3''-O-β-D-glucopyranoside, moracin O-3'-O-β-D-xylopyranoside, moracin P-2''-O-β-D-glucopyranoside, moracin P-3'-O-β-D-glucopyranoside, moracin P-3'-O-α-L-arabinopyranoside, moracin P-3'-O-[β-D-glucopyranosyl-(1→2)]-α-L-arabinopyranoside		Zheng XK, Cao YG, Ke YY, Zhang YL, Li F, Gong JH, Zhao X, Kuang HX, Feng WS. Phenolic constituents from the root bark of Morus alba L. and their cardioprotective activity in vitro. Phytochemistry. 2017 Mar;135:128-134. PubMed
phenolic	2,4-dihydroxy-5-(4-hydroxybenzyl) benzoic acid, 2,4-dihydroxy-5-(3,4-dihydroxybenzyl) benzoic acid		Zheng XK, Cao YG, Ke YY, Zhang YL, Li F, Gong JH, Zhao X, Kuang HX, Feng WS. Phenolic constituents from the root bark of Morus alba L. and their cardioprotective activity in vitro. Phytochemistry. 2017 Mar;135:128-134. PubMed
flavonoid	sanggenon U (1), sanggenon V (2), sanggenon W (3)		Jung JW, Park JH, Lee YG, Seo KH, Oh EJ, Lee DY, Lim DW, Han D, Baek NI. Three New Isoprenylated Flavonoids from the Root Bark of Morus alba. Jung JW, Park JH, Lee YG, Seo KH, Oh EJ, Lee DY, Lim DW, Han D, Baek NI. Molecules. 2016 Aug 24;21(9). PubMed
flavonoid	soroceal B (1), sanggenol Q (7)		Qin J, Fan M, He J, Wu XD, Peng LY, Su J, Cheng X, Li Y, Kong LM, Li RT, Zhao QS. New cytotoxic and anti-inflammatory compounds isolated from Morus alba L. Nat Prod Res. 2015;29(18):1711-8. PubMed
benzofuran	(2''R)-(-)-moracin-O-5',3''-β-D-diglucopyranoside (1), (2''R)-(-)-moracin-P-5',2''-β-d-diglucopyranoside (2)		Park JH, Jung YJ, Jung JW, Shrestha S, Han D, Lim DW, Baek NI. Two new isoarylbenzofuran diglucosides from the root bark of Morus alba. J Asian Nat Prod Res. 2015;17(4):357-63. PubMed
phenolic	(2R,3S)-guibourtinidol-3-O-α-d-apiofuranosyl-(1→6)-O-β-D-glucopyranoside (1)		Park JH, Jung YJ, Jung JW, Shrestha S, Lim DW, Han D, Baek NI. A new flavonoid glycoside from the root bark of Morus alba L. Nat Prod Res. 2014;28(21):1859-63. PubMed
flavonoid	(2S)-4'-hydroxy-7-methoxy-8-prenylflavan		Yang Y, Yang X, Xu B, Zeng G, Tan J, He X, Hu C, Zhou Y. Chemical constituents of Morus alba L. and their inhibitory effect on 3T3-L1 preadipocyte proliferation and differentiation. Fitoterapia. 2014 Oct;98:222-7. PubMed
triterpenoid	lup-20(29)-en-3β-ol-27-oic acid (moruslupenoic acid A), lup-12, 20(29)-dien-3β-ol-26-oic acid (moruslupenoic acid B), lanst-5, 24-dien-3β-yl acetate (moruslanosteryl acetate)		Ali A, Ali M. New triterpenoids from Morus alba L. stem bark. Nat Prod Res. 2013;27(6):524-31. PubMed
flavonoid	3'-geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone		Dat NT, Binh PT, Quynh le TP, Van Minh C, Huong HT, Lee JJ. Cytotoxic prenylated flavonoids from Morus alba. Fitoterapia. 2010 Dec;81(8):1224-7. PubMed

약리정보

* 질병 분류 별 논문 수

질병 분류	임상 시험 human	동물 실험 in vivo	세포 및 시험관 실험 in vitro	total (건)
종양(II)	0	1	0	1
혈액 및 혈액 생성 기관 질병으로 면역 체계와 관련된 병(III)	0	1	0	1
내분비선 영양 및 순환계(IV)	0	6	0	6
피부와 피하 조직의 질병(XII)	0	1	1	2
생식, 배설 계통의 질병(XIV)	0	1	0	1
상처, 중독과 외부 원인에 의한 것들(XIX)	0	1	0	1
항산화 또는 항염증(XXIII)	0	1	1	2
합계	0	12	2	14

*숫자를 클릭하면 약리작용 상세정보를 볼 수 있습니다.

사진