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| Oxford COVID-19 Evidence Service |
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Oxford COVID-19 Evidence Service 출처: CEBM(The Centre for Evidence-Based Medicine) University of OXFORD The CEBM has committed its skills and expertise in evidence synthesis and dissemination to support the current COVID-19 pandemic. How do you manage pneumonia in older people in a pandemic? 팬더믹에서 고령층의 폐렴을 어떻게 관리하나요? ￭ Read: Rapidly managing pneumonia in older people during a pandemic https://www.cebm.net/rapidly-managing-pneumonia-in-older-people-during-a-pandemic/ ￭ Pneumonia treatment in the elderly PDF to download What trials are being done, which interventions might work? Answer due 17th March 무슨 중재로 어떻게 임상시험이 진행되고 있나요? ￭ Read: COVID-19 trials registered up to 8 March 2020—an analysis of 382 studies We downloaded the listings of these 382 registered trials and classified them to aid interpretation of the type of interventions being proposed. Do NSAIDs worsen outcomes in acute respiratory infections (ARI)? NSAID의 사용이 급성 호흡기 감염(ARI)의 결과를 악화시키나요? Responding to the Guardian: Anti-inflammatories may aggravate Covid-19, France advises Verdict: there is a need for caution when using NSAIDs in the context of acute respiratory infections (ARI). Pre-existing medications and conditions need to be taken account of when deciding to prescribe NSAIDs for symptomatic ARI. The lowest effective dose should be prescribed for the shortest period of time. Parenteral use of NSAIDs during an ARI should be avoided. NSAIDs do not significantly reduce total symptoms or duration of respiratory infections. ￭ Read: NSAIDs in Acute Respiratory Infection What’s the evidence for social distancing? Answer due 18th March 사회적 거리두기의 근거는 무엇인가요? Should you treat a high temperature in acute respiratory infections? Answer due 19th March 급성 호흡기 감염에서 고열을 치료해야 하나요? ￭ Read: Assessment of Mortality in the Covid-19 outbreak In an outbreak, understanding the impact on overall rates of death can provide vital information about the effect in the population at large. See the latest mortality update here Update March 17th: today’s data release refers to the week ending the 6th March and remains relatively unchanged: ￭ Total deaths all ages 10,895 (last weeks 10,816) ￭ Over the previous 5 years 11,498 (RR still trending 3% less, p=0.134) ￭ Respiratory deaths 1,517 for week 9 (up to 28th Feb) no change on the previous week ￭ Deaths in over 85s 4,361 no change on last week (4,414) ￭ Read: Assessment of the Global Covid-19 Case Fatality Rates? What is the evidence for Hand Disinfectant and COVID-19? COVID-19에서 손 소독제 사용의 근거는 무엇인가요? Read: Hand Disinfectant and COVID-19 Physical interventions to interrupt or reduce the spread of respiratory viruses report a near 50% reduction in respiratory infections in those who washed their hands frequently. Current questions under review: What is the effect of ACE-I/ARB and pneumonia in Covid-19? Mark A. Graber, University of Iowa Carver College of Medicine In adults and children does suppressing fever in ARI affect outcomes? Sophie Park, UCL Should you Stop ACE/ARBs prior to infection? Richard Hobbs, NDPHCs Should you add ACE/ARB if you get infected with COVD-19? Richard Hobbs, NDPHCs Are inhaled steroids in asthma OK to continue with or should you stop them? Richard Hobbs, NDPHCS Evidence Service Team: Jeff Aronson (CEBM), Robin Ferner UoB), Richard Hobbs (NDPHCs) Kamal Mahtani (CEBM), Nicholas DeVito (EBM DataLab), Jon Brassey, (TripDatabase), Annette Pluddemann, Carl Heneghan (CEBM) If you have a question that you would like our service to answer then contact cebm@phc.ox.ac.uk The Evidence COVID-19 Service is supported by the NIHR SPCR Evidence Synthesis Working Group [Project 390] Cite this resource as: Oxford COVID-19 Evidence Service. https://www.cebm.net/oxford-covid-19/ Latest Coronavirus News and Analysis from the Department of Primary Care |