KMCRIC

According to a review, motherwort has been used traditionally to treat insomnia and anxiety and theoretically may interact with other sedatives [​1​]. According to secondary sources, motherwort my cause drowsiness and theoretically may have additive effects with CNS depressants and sedatives such as clonazepam ((Klonopin®), lorazepam (Ativan®), phenobarbital (Donnatal®), and zolpidem (Ambien®).

... 따르면, 익모초는 전통적으로 불면증과 불안을 치료하는데 사용하고 있으며 이론적으로 다른 진정제와 상호 작용할 수 있다 [​1​]. 2차 출처에 따르면, 익모초는 졸음을 일으킬 수 있으며 중추 신경계 (CNS) 억제제 및...

Combination use of caffeine and other stimulants may theoretically result in additive stimulant effects and increase the risk of adverse effects such hypertension, tachycardia, insomnia, and nervousness. There is a case report of ischemic stroke after intranasal use of amphetamine and caffeine [​27​]. In animals, caffeine may potentiate the reinforcing and discriminative effects of cocaine [​140​;​141​;​142​;​143​]. In humans, there was a lack of physiologic response to cocaine with infrequent acute caffeine administration, with the exception of augmenting blood pressure [​144​]. In humans, combined use of phenylpropanolamine and caffeine may result in increases in blood pressure [​145​;​146​;​147​;​148​;​149​;​150​], which may be due to pharmacokinetic and pharmacodynamic mechanisms [​149​]. It has also been shown to have additive effects on cardiovascular parameters with nicotine (549). In animal research, coadministration of caffeine and methylphenidate resulted in long-term changes in locomotor activity and cross-sensitization through dopamine- and cAMP-regulated phosphoproteins of the 32kDa (DARPP-32)-dependent pathway [​152​].

... 다른 자극제를 함께 사용하는 것은 이론적으로 부가적인 자극 효능을 초래하며 고혈압, 빈맥, 불면증, 불안과 같은 유해 효과의 위험을 증가시킬 수있다. 암페타민과 카페인의 비강 내 사용에 따른 허혈성...

Gastrodia elata(GE) aqueous extract decreased amyloid-β peptide (Aβ)-induced PC12 cells` death with GE treatment at ≤10 mg/mL in a dose-dependent manner. Also, Oral administraion of GE extract(50, 250 and 500 mg/kg for 6 weeks) improved learning and memory capability assessed by...

... 세포사를 10mg/mL 이하에서 농도의존적으로 감소시킴. 2) 또한, 6주 동안 50, 250, 500mg/kg의 천마 추출액 경구투여는 scopolamine (1mg/kg)이 주입된 불면증 모델 흰쥐에서 행동기능 검사를 하였을 때 학습 및 기억 능력을 개선시킴....