KMCRIC

In vitro, Drynol Cibotin, a combination product containing angelica, soy, wild yam, Ligustrum, astragalus, Cuscuta chinensis, Psoraleae corylifoliae, and Drynaria fortune, purportedly increased calcium uptake [​104​].

In vitro 연구에서, 안젤리카, 콩, 야생 참마, 광나무, 황기, 갯실새삼, 보골지, 곡궐로 구성된 Drynol Cibotin은 칼슘의 흡수를 증가시켰다 [​104​].

Dong quai may interfere with progesterone, tamoxifen, or raloxifene binding to estrogen receptors [​15​]. Dong quai may stimulate the corpora lutea to secrete progesterone [​29​;​30​]. In vitro biochemical research on the bioactivity of dong quai showed little estrogen receptor binding [​31​]. Saliva from women taking dong quai was found to have low estradiol levels [​31​]. Dong quai may competitively inhibit estradiol binding to estrogen receptors, increase ceruloplasmin oxidase activity, and decrease luteinizing hormone levels [​32​]. In rats, Angelica sinensis had estrogenic effects [​33​;​34​]. In a human research, dong quai water extract combined with 17beta-estradiol stimulated the proliferation of MCF-7 cells by weak estrogen-agonist effects, and demonstrated growth stimulation effects on BT-20 cells with or without 17beta-estradiol [​35​].

... 생리 활성에 대한 시험관 내 생화학적 연구에서 에스트로겐 수용체 결합이 거의 보이지 않았다 [​31​]. 중국당귀를 복용하는 여성들의 침에서 에스트라디올의 수치가 낮은 것으로 나타났다 [​31​]. 중국당귀는...

Decursin and decursinol are probably active/prodrug compounds against TRAMP epithelial lesions, and they cooperate with non-pyranocoumarin compounds to fully express Angelica gigas Nakai efficacy against NE-Ca.

당귀 Decursin과 Decursinol angelate는 전립선 암 쥐 모델의 상피 병변에 대해 활성/전구 물질이 될 수 있으며 신경내분비암종에 대해 당귀의 비 피라노쿠마린 계열 화합물들과 협력함.

Angelan may be useful to immunotherapies against cancer because it induces T-cell and dendritic cell maturation via activating ERK and NF-kappaB, which are signaling molecules down-stream of toll-like receptor-4 (TLR4) receptors.

당귀 Angelan은 T 세포와 톨유사수용체-4의 신호전달 분자인 ERK와 핵인자카파비의 활성화를 통해 면역 반응을 일으켜 암세포사멸을 유도함.