KMCRIC

In psychiatric inpatients, the use of polypharmacy and valproic acid, individually, were associated with low serum carnitine levels [​1​]. Diao et al. discussed the quantitative structure activity relationship for inhibition of the human organic cation/carnitine transporter (OCTN2) [​2​]. Sinicropi et al. examined the behavior of acetyl-L-carnitine injections (Nicetile fiale) in combination with different drugs used for combined therapy [​3​]. The authors concluded that the content of all the active drugs after mixing remained optimal, within 10% of their nominal values. Diao et al. discussed novel inhibitors of OCTN2 based on computational modeling and in vitro testing [​4​]. It was determined that compounds were more likely to cause rhabdomyolysis if the C(max):K(i) ratio was higher than 0.0025.

정신과 입원환자에게서, 다약제 복용과 발프로산 (valproic acid)의 개별적인 사용은, 낮은 혈청 카르니틴 수치와 관련이 있었다 [​1​]. Diao et al.은 사람의 유기 양이온/카르니틴 운반자 2 (organic cation/carnitione transporter 2, OCTN2)의...

In available clinical research, benefit of cannabis-based therapies in cancer-related anorexia-cachexia syndrome was lacking [​54​]; however, early research suggests a benefit of dronabinol on weight gain in patients with cystic fibrosis [​55​] and on appetite and weight in patients with AIDS [​56​]. In patients with eating disorders, THC had a lack of effect on weight, caloric intake, and psychiatric assessment [​57​].

... 섬유증 환자의 체중 증가 [​55​] 및 후천성 면역 결핍증 환자의 식욕과 체중에 [​56​] 대한 드로나비놀의 이점을 제시한다. 섭식 장애 환자에게서, 체중, 칼로리 섭취량, 및 정신과 평가에 대한 THC의 효과는 부족했다 [​57​]....